Experimental Models of Vaginal Candidiasis and Their Relevance to Human Candidiasis
نویسندگان
چکیده
منابع مشابه
Microscopic features of vaginal candidiasis and their relation to symptomatology.
OBJECTIVES To document the microscopic features of vaginal candidiasis and to examine the relation between yeast morphology and patient symptomatology. METHOD The study population comprised women undergoing screening for genital infection at a department of genitourinary medicine. RESULTS/CONCLUSION Data were collected on 267 women of whom 234 were found to have vaginal candidiasis by vagin...
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Studies with an estrogen-dependent murine model of vaginal candidiasis suggest that local cell-mediated immunity (CMI) is more important than systemic CMI for protection against vaginitis. The present study, however, showed that, compared to uninfected mice, little to no change in the percentage or types of vaginal T cells occurred during a primary vaginal infection or during a secondary vagina...
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Recurrent vaginal candidiasis is one of the most common reasons for patients visiting their primary care doctors. Majority of the cases are caused by Candida albicans. Controlling of risk factors such as diabetes mellitus, used of broad spectrum antibiotics, contraceptive pills and steroid therapy helps in managing recurrent vaginal candidiasis. Initial 14-day course of oral azoles and followed...
متن کاملExperimental In Vivo Models of Candidiasis
Candidiasis is a multifaceted fungal disease including mucosal-cutaneous, visceral, and disseminated infections caused by yeast species of the genus Candida. Candida infections are among the most common human mycoses. Candida species are the third to fourth most common isolates from bloodstream infections in neutropenic or immunocompromised hospitalized patients. The mucosal-cutaneous forms-par...
متن کاملEffects of reproductive hormones on experimental vaginal candidiasis.
Vulvovaginal candidiasis (VVC) is an opportunistic mucosal infection caused by Candida albicans that affects large numbers of otherwise healthy women of childbearing age. Acute episodes of VVC often occur during pregnancy and during the luteal phase of the menstrual cycle, when levels of progesterone and estrogen are elevated. Although estrogen-dependent experimental rodent models of C. albican...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2016
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.01544-15